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As demonstrated in a previous study (Hendgen-Cotta et al., 2017), BNIP3 and NIX form homo/heterodimers to maintain mitochondrial homeostasis and interact with Mieap (mitochondrial engulfment protein) and CDH6 (cadherin 6) to regulate ROS clearance and Drp1-mediated fission (Nakamura et al., 2012)

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